Import data and price of benzyl chloroformate under hs. Also used in a recently reported 3step synthesis of 1,2,4oxadiazoles. Benzyl chloroformate is a lachrymator that can cause serious damage to eyes and skin on contact. It is a mono substituted benzene derivative, consisting of a ch3 group attached to a phenyl group.
Benzyl alcohol prepared from toluene by heating it with kmno4 and na2co3 in aqu. Precautionary statements p210 keep away from heat, hot surfaces, sparks, open flames and other. Benzyl chloroformate also known as benzyloxycarbonyl chloride, benzyl chlorocarbonate, carbobenzoxy chloride, carbonochloridic acid phenylmethyl ester, and zchloride, and represent with the linear formula clco2ch2c6h5, which is a clear light oily liquid, and variants its color to yellow to colorless, although it is also known for its pungent odor. Alkoxy carbamate synthesis and stimulusresponsive alcohol release r.
Diethyl ether material safety data sheet cas no 6029. Benzylchloroformate 50 % solution in toluene, 501531, laboratory chemicals, c8h7clo2 by loba chemie, india. Control parameters sampling time update methyl mercaptan 74931 methemoglobin. Carbobenzoxy chloride, zchloride cas number 501531.
Benzyl chloroformate 501531 buy and find out price and availability, msds, properties of. Attacks many metals especially in humid atmosphere handling chemicals safely 1980. Polyethylene is susceptible to attack by some chemicals which may cause stress cracking, swelling, oxidation or may permeate the polyethylene. How is benzyl alcohol prepared from toluene oxidation. Benzylchloroformate 50% solution in toluene, 501531, laboratory chemicals, c8h7clo2 by loba chemie, india. In case of fire, smoke and other combustion products carbon monoxide, carbon dioxide and benzyl chloride may be formed, the inhalation of such combustion products.
Also known as benzyl chlorocarbonate it is an oily colorless liquid although impure samples appear yellow. The benzylation of toluene with benzyl chloride was studied at 383 k in the liquid phase on different protonic zeolites. Benzyl alcohol wikimili, the best wikipedia reader. Toluene also known as toluol is an aromatic hydrocarbon. Benzyl acetate is an organic compound with the molecular formula c 9 h 10 o 2.
Benzyl chloroformate is also a suspected carcinogen. Benzyl chloroformate, 50 wt% solution in toluene catalog numbers. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Extra dry solvents deuterated solvents organometallic. On this page you will be able to access individual acute exposure guideline level aegls values that are intended to protect most individuals in the general population, including those that might be particularly susceptible to the harmful effects of the chemicals. A list of common conditions for cbz protection and deprotection in organic chemistry. Benzyl chloroformate is the benzyl ester of chloroformic acid. Benzyl acetate is also known as acetic acid, benzyl ester, acetic acid. The compound can be viewed as the ester of carbamic acid ocohnh 2 and benzyl alcohol, although it is produced from benzyl chloroformate with ammonia. Attach the empty distilling column as an air condenser. This listing was prepared to provide guidance to the chemical compatibility molded polyethylene. Firstaid measures general advice show this safety data sheet to the doctor in attendance. Eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Nontoxic in contact with skin ld50 skin 5000 mg kg.
Benzyl chloroformate, 3m 50 wt% solution in toluene bzcf. Access acute exposure guideline levels aegls values. Material safety data sheet benzyl chloride msds finar limited. Call a physician or poison control center immediately. Benzyl chloroformate 50 % in toluene a colourless to lightyellow liquid that is used as an intermediate in apis.
The 2016 emergency response guidebook, developed jointly by transport canada tc, the u. Benzyl chloroformate market research report forecast to. Safety data sheet according to 29cfr19101200 and ghs rev. By integrating people, technology and potential, we endeavor to make contribution to the betterment of human society. Synonym, chloroformic acid benzyl ester 3035% in toluene. Benzyl chloroformate, 3m 50 wt% solution in toluene 100ml 42890 benzyl chloroformate, technical grade, 97% 100ml 43077 800ml 430778000 benzylmagnesium chloride, 1. Benzyl chloroformate solution technical, 50% in toluene sigma. Benzyl chloroformate 50% solution in toluene 501531. Nonphosgene synthesis of benzyl chloroformate cbzcl. Identification of the substancemixture and of the companyundertaking.
Articles of benzyl 1cyano1 methylethylcarbamate are included as well. Toluene 108883 50 benzyl chloroformate 501531 50 benzyl chloride 100447 0. Benzyl chloroformate c8h7clo2 cid 10387 structure, chemical names, physical and chemical. Benzylation of toluene by benzyl chloride over protonic. The substance identity section is calculated from substance identification information from all echa databases. Benzyl chloroformate cbzcl 1a was introduced by bergmann and zervas about 70 years ago for a nprotective reagent for amino group in peptide synthesis. Cbzprotected anilines were prepared directly from aromatic carboxylic acids, sodium azide and cbzcl. Benzyl chloroformate solution technical, 50% in toluene. Methyl mercaptan 74931 immediately dangerous to life or health concentration value 150 parts per million 19950301 us substance name casno. Synthesis of benzyl acetate to a reaction tube add 540 mg of benzyl alcohol and 510 mg of acetic anhydride and a boiling chip.
Benzyl chloroformate 501531 msds, safety technical. Benzylcarbonyl chloride benzyl chlorocarbonate carbobenzoxy chloride chloroformic acid, benzyl ester restrict access. Ascabin ascabiol benylate benzyl alcohol benzoic ester benzyl benzenecarboxylate. Inhalation is very harmful to the upper respiratory tract and lungs, and may be fatal if exposure is sufficient. Lot and batch numbers can be found on a products label following the words lot or batch. Benzyl carbamate is the organic compound with the formula c 6 h 5 ch 2 oconh 2. Structure, properties, spectra, suppliers and links for. Benzyl chloroformate 501531 msds report, benzyl chloroformate msds safety technical specifications search, benzyl chloroformate safety information specifications ect. It is a white solid that is soluble in organic solvents and moderately soluble in water. Loosen clothing and place exposed in a comfortable position.
When discolored phosgene was used probably containing iron salts from corrosion of the cylinder, a violent explosion occurred during the distillation phase, presumably. To estimate kinetic parameters for toluene reaction with benzyl alcohol. Monobenzylation to benzyltoluenes is the main reaction, usually higher than 90% selectivity when a toluenebenzyl chloride molar ratio of 5 is used. It is the ester formed by condensation of benzyl alcohol and acetic acid. It is useful for the introduction of carboxybenzyl cbz protecting group for amines such as aniline in organic synthesis. View detailed import data, price, monthly trends, major importing countries, major ports of benzyl chloroformate under hs code 2915. R e f e r e n c e i n f o r m a t i o n threshold limit values tlv and immediately dangerous to life and health idlh values. Safety data sheet according to federal register vol. In case of accident or if you feel unwell, seek medical advice immediately show the label where possible. We develop, produce and distribute high quality pharmaceutical chemicals, special chemicals and other fine chemicals.
The substance identifiers displayed in the infocard are the best available substance name, ec number, cas number andor the. Benzyl chloroformate solution technical, 50 % in toluene synonym. After cooling, the colorless crystalline solid was isolated by filtration, washed with cold toluene, and recrystallized from ethanol. Benzyl chloroformate is widely used as a reactive chemical intermediate in plastic, pharmaceutical, agricultural and organic chemicals. Compatibility chemical compatibility chemicial compatibility guide the following information is intended to be used as a general guideline for pump material selection. Reflux the resulting mixture for 1 h or more, then cool it to room temperature. It is a colorless, water insoluble liquid with the smell associated with paint thinners.
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